They will work together (kind of) without the GAD 29 but you will forego a lot of the functions that you bought the G3X for. The 2" navigators do not have a CAN interface which is the backbone of the whole G3X system. The GAD 29 provides that interface.
There are several interfaces, some of which use the ARINC/CANbus link (via GAD29) and some which are wired direct on RS232 links. If they are not all present then some functionality will be lost. GAD 29 provides Airdata to the Txpdr side of the GNX (to support ADSB) and sends nav data to the GDU.