Wiring hole location
I would run the wires through a single place aft of the spar. The benefit there is you can inspect them or access them from the inspection panels on the wing bottom. Put them far enough aft to avoid any interference with the aileron push/pull tube.
I have had no noise issues but if you are concerned, separate the runs. Besides heated pitot, allow for aileron trim, strobes, position, and landing lights, and any antennas in the wing tip.
For what itís worth, I did not use conduit here because the rib spacing allowed a lot of support. It is clearly an option, however.
RV-10 and Breezy