Didn't Mobil pay out huge damage claims in the '80's when they sold Mobil 1 for aircraft? I think the problem was that full-synthetic oil couldn't keep the lead from the fuel in suspension adequately, and that's why there's no full-synthetic aircraft oil out there today.
Like Harvey Sorensen above, I too filled the sump of my 2000-hour IO-360 with Shell Rotella oil in an effort to help the cam lobes and other internals after the engine had been sitting for 8+ years since last run. My reasoning for not overhauling before first flight was that the engine was a known quantity (unlike the 0-hour airframe), and I could putz around at low power settings during the initial flight test period. I ran the engine for about an hour total on the ground before changing to Aeroshell W100.
Well, I'm not sure I did the right thing by doing that. After the first 5 hours of flight, I removed and cut open the filter. There was a HUGE amount of carbon particles in there, almost certainly the result of running the high-detergent oil for an hour. No metal, fortunately. I changed the oil at the 44-hour mark and found normal amounts of debris in the filter that time.
Why did I say that wasn't the right thing to do? Because I recently did a leak-down test and found two cylinders 55/80 and one at 65 and one at 70. At the last annual (while still bolted to the donor Mooney), the numbers were all in the mid- 70's. I'm thinking the carbon came mostly from the ring lands causing the rings to have shifted position and are no longer sealing as well as they used to. In time, that may get better again. There's still very little blow-by (clean belly) and oil consumption is about 6 hours/qt, the same as it was on the Mooney. Either way, I'm planning on overhauling the thing this winter which will make that a moot point.
Just another thing to think about.
Heinrich Gerhardt
RV-6 with all of 54 hours...